This test assesses metabolism of the essential amino acid methionine (Met). Methionine is paramount in two metabolic processes:
Firstly, transmethylation which is critical for the methylation of hundreds of importantmolecules such as DNA, RNA, proteins, neurotransmitters and membrane phosphatidylcholine, and secondly transsulphuration which leads to the biosynthesis of cysteine and hence glutathione, both of which have manyimportant protective/detoxification functions. Aberrant Met metabolism can be caused by nutritionaldeficiencies, exposures to environmental toxicants and/or genetic polymorphisms and can have significantadverse health consequences. Identification of such abnormalities can guide appropriate nutritionalintervention towards normalization of methionine metabolism and decreased risk and incidence of adversehealth effects.
Note: Unless your practitioner can centrifuged and freeze your sample for you, you will need to attend Biolab in London for this test.
Overnight fast and avoid methionine, cysteine, and SAMe supplements for 48 hours prior to the test.
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